2016

Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F (2016). Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nature Biotechnology. On-line Feb 22. doi: 10.1038/nbt.3467. PubMed

Gebler C, Lohoff T, Paszkowski-Rogacz M, Mircetic J, Chakraborty D, Camgoz A, Hamann MV, Theis M, Thiede C, Buchholz F (2016). Inactivations of cancer mutations utilizing CRISPR/Cas9. JNCI. doi: 10.1093/jnci/djw183. PubMed

Karimova M, Splith V, Karpinski J, Pisabarro MT, Buchholz F (2016). Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering. Sci Rep. 2016 Jul 22;6:30130. doi: 10.1038/srep30130. PubMed

Meinke G, Bohm A, Hauber J, Pisabarro MT, Buchholz F (2016). Cre Recombinase and Other Tyrosine Recombinases. Chem Rev. May 10. PubMed

Herberg M, Glauche I, Zerjatke T, Winzi M, Buchholz F, Roeder I (2016). Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics. J R Soc Interface. Apr;13(117). pii: 20160167. doi: 10.1098/rsif.2016.0167. PubMed

Linge A, Lohaus F, Löck S, Nowak A, Gudziol V, Valentini C, von Neubeck C, Jütz M, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Grosu AL, Abdollahi A, Debus J, Ganswindt U, Belka C, Pigorsch S, Combs SE, Mönnich D, Zips D, Buchholz F, Aust DE, Baretton GB, Thames HD, Dubrovska A, Alsner J, Overgaard J, Krause M, Baumann M; DKTK-ROG (2016). HPV status, cancer stem cell marker expression, hypoxia gene signatures and tumour volume identify good prognosis subgroups in patients with HNSCC after primary radiochemotherapy: A multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group (DKTK-ROG). Radiother Oncol. Dec;121(3):364-373. doi: 10.1016/j.radonc.2016.11.008. PubMed

Linge A, Löck S, Gudziol V, Nowak A, Lohaus F, von Neubeck C, Jütz M, Abdollahi A, Debus J, Tinhofer I, Budach V, Sak A, Stuschke M, Balermpas P, Rödel C, Avlar M, Grosu AL, Bayer C, Belka C, Pigorsch S, Combs SE, Welz S, Zips D, Buchholz F, Aust DE, Baretton GB, Thames HD, Dubrovska A, Alsner J, Overgaard J, Baumann M, Krause M; DKTK-ROG (2016). Low Cancer Stem Cell Marker Expression and Low Hypoxia Identify Good Prognosis Subgroups in HPV(-) HNSCC after Postoperative Radiochemotherapy: A Multicenter Study of the DKTK-ROG. Clin Cancer Res. Jun 1;22(11):2639-49. doi: 10.1158/1078-0432.CCR-15-1990. PubMed

Bäumer N, Appel N, Terheyden L, Buchholz F, Rossig C, Müller-Tidow C, Berdel WE, Bäumer S (2016). Antibody-coupled siRNA as an efficient method for in vivo mRNA knockdown. Nat Protoc. Jan;11(1):22-36. doi: 10.1038/nprot.2015.137. PubMed

Buchholz F, HauberJ (2016). Antiviral therapy of persistent viral infection using genome editing. Curr Opin Viro. Oct 7;20:85-91. doi: 10.1016/j.coviro.2016.09.012. PubMed