2015

Schmitt-Engel C, Schultheis D, Schwirz J, Ströhlein N, Troelenberg N, Majumdar U, Anh Dao V, Grossmann D, Richter T, Tech M, Dönitz J, Gerischer L, Theis M, Schild I, Trauner J, Koniszewski NDB, Küster E, Kittelmann S, Hu Y, Lehmann S, Siemanowski J, Ulrich J, Panfilio KA, Schröder R, Morgenstern B, Stanke M, Buchholz F, Frasch M, Roth S, Wimmer EA, Schoppmeier M, Klingler M, Bucher G (2015). The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology. Nature Communications. Jul 28. PubMed

Bäumer S, Bäumer N, Appel N, Terheyden L, Fremerey J, Schelhaas S, Wardelmann E, Buchholz F, Berdel WE, Müller-Tidow C (2015). Antibody-mediated delivery of anti-KRAS-siRNA in vivo overcomes therapy resistance in colon cancer. Clinical Cancer Research. Mar 15. PubMed

Theis M, Paszkowski-Rogacz M, Weisswange I, Chakraborty D, Buchholz F (2015). Targeting Human Long Noncoding Transcripts by Endoribonuclease-Prepared siRNAs. J Biomol Screen Mar 15;21(6):1383-94 PubMed

Wermke M, Camgoz A, Paszkowski-Rogacz M, Thieme S, von Bonin M, Dahl A, Platzbecker U, Theis M, Ehninger G, Brenner S, Bornhäuser M, Buchholz F (2015). RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug. Blood Jun 11;125(24):3760-8. PubMed

Karimova M, Beschorner N, Dammermann W, Chemnitz J, Indenbirken D, Bockmann JH, Grundhoff A, Lüth S, Buchholz F, Schulze zur Wiesch J, Hauber J (2015). CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X. Science Reports Sep 3;5:13734. PubMed

Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M (2015). A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Oct 22; 163(3):712-23. PubMed

Bäumer N, Appel N, Terheyden L, Buchholz F., Rossig C, Müller-Tidow C, Berdel WE, Bäumer S (2015). Antibody-coupled siRNA as an efficient method for in vivo mRNA knockdown. Nature Protocols Dec 3; (1):22-36. PubMed

Ding L, Paszkowski-Rogacz M, Winzi M, Chakraborty D, Theis M, Singh S, Ciotta G, Poser I, Roguev A, Chu WK, Choudhary C, Mann M, Stewart AF, Krogan N, Buchholz F (2015). Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells. Cell Systems Aug 26. PubMed

Appel N, Bäumer N, Wardelmann E, Buchholz F, Müller-Tidow C, Berdel WE, Bäumer S (2015). Molecular targeting of EGFR-downstream effectors in colorectal cancer cells by antibody-mediated siRNA treatment. Oncol Res. Treat Aug 26;38(suppl 5):1-288. Oncol Res Treat