Frank Buchholz and members of his research group attended the 30th Annual Meeting of the German Society for Gene Therapy (DG-GT), titled Nucleic Acid Therapeutics: Genetic Indications and Beyond held in Munich, March 6-8.
During the session on Novel Concepts in Genome Engineering, Frank Buchholz shared insights into the latest advancements in designer recombinases, highlighting the potential of next-generation tools in this field. Jenna Hoersten presented a poster focusing on the critical aspects of off-target analysis and mitigation strategies to enhance the efficiency of recombinases. Additionally, Duran Sürün unveiled his research through a poster on CRISPR-Associated Substrate-Linked Directed Evolution (CaSLiDE), a novel approach aimed at developing highly efficient and specific miniature CRISPR-Cas systems.